|
|
|
MAPTrix¢â ECM Coating Kit
|
|
|
|
|
 MAPTrix¢â ECM based coatings or surface modification is simple, convenient and highly reproducible. You can readily engineer a synthetic ECM surface that binds to adhesion receptors such as integrins and promote cell adhesion and spreading.
MAPTrix¢â ECM line of flexible products can be used in your cell culture applications alone or in combination with other products.
|
|
Product Features
|
|
|
|
|
- Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
- Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable
- MAPTrix¢â produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
- Kollodis BioSciences currently provides a wide array of MAPTrix¢â ECM products (115 ECM lines)
|
|
MAPTrix¢â ECM Line of Product
|
|
|
|
|
Kollodis BioSciences currently provides a wide array of MAPTrixTM ECM products in its expanding MAPTrix¢â ECM line of products. The following table summarize typical example of MAPTrix¢â ECM line of products.
Download MAPTrix¢â ECM Library for our complete list of MAPTrix¢â ECM.
|
|
|
|
|
|
ECM Component
|
|
MAPTrix¢â ECM
Mimetic |
|
Origin of
Peptide Motif |
|
Typical Peptide Motif in MAPTrix¢â ECM (partial list) |
|
|
|
Collagen
|
|
MAPTrix¢â C |
|
Type I
Type III
Type IV |
| GFPGER, GLPGER, DGEA, GTPGPQGIAGQRGVV, KGHRGF, GASGER, GAPGER
GLKGEN, GLPGEN
TAGSCLRKFSTM, GEFYFDLRLKGDK, FYFDLR, MNYYSNS, TAIPSCPEGTVPLYS
|
|
|
|
Fibronectin
|
|
MAPTrix¢â F |
|
Type III
Type III CS
FN-C/H (III, IV, V) |
| KLDAPT, PHSRN, PHSRN-RGDSP, GRGDSP
EILDVPST, REDV
SPPRRARVT, WQPPRARI, KNNQKSEPLIGRKKT
|
|
|
|
Laminin
|
|
MAPTrix¢â L |
|
¥á1 chain
¥á3 chain
¥á5 chain
¥â1 chain
¥ã chain |
| IKVAV, RQVFQVAYIIIKA, NRWHSIYITRFG, TWYKIAFQRNRK, RKRLQVQLSIRT
KNSFMALYLSKGRLVFALG
GIIFFL
YIGSR, RYVVLPR
KAFDITYVRLKF, RNIAEIIKDI
|
|
|
|
Vitronectin
|
|
MAPTrix¢â V |
|
HBV |
| KKQRFRHRNRKGYRSQ
FRHRNRKGY
|
|
|
|
Cadherin
|
|
MAPTrix¢â E |
|
E-cadherin
N-cadherin |
| LFSHAVSSNG, ADTPPV, DQNDN
HAVDI, LRAHAVDING
|
|
|
|
Miscellaneous
|
|
MAPTrix¢â M
MAPTrix¢â S |
|
Nidogen
Fibrinogen
Elastin
Bone sialoprotein
Osteopontin
Tenascin-C
|
| LNRQELFPFG, SIGFRGDGQTC
HHLGGAKQAGDV
VGVAPG, PGVGV
FHRRIKA, KRSR
SVVYGLR
VAEIDGIEL, VFDNFVLK
|
|
|
|
|
|
|
MAPTrix¢â ECM Line of Product for engineering stem cell microenvironment
|
|
|
|
|
|
|
MAPTrix¢â ECM
Product
|
|
Peptide Motif |
|
Target Integrin |
|
Functionality |
|
Cell Line |
|
Reference |
|
|
|
MAPTrix¢â F
|
|
GRGDSP
WQPPRARI |
|
¥á5¥â1
heparin |
| Self-renewal |
| H1, H7, H9, H13, H14 |
| Nature Methods (2010) |
|
|
|
MAPTrix¢â L
|
|
NRWHSIYITRFG
TWYKIAFQRNRK |
|
¥á6¥â1
¥á6¥â1 |
| Self-renewal & long term expansion |
| H1 |
| FASEB J. (2010) |
|
|
|
MAPTrix¢â L
|
|
RYVVLPR
LGTIPG |
|
heparin
unknown |
| Self-renewal and proliferation without differentiation potential |
| H1, H9 |
| ACS Bio Chem (2007) |
|
|
|
MAPTrix¢â L
|
|
KAFDITYVRLKF
TSIKIRGTYSER |
|
¥áv¥â3
unknown |
| Self-renewal & long term expansion |
| H1, H9 |
| Biomaterials (2012) |
|
|
|
MAPTrix¢â V
|
|
GKKQRFRHRNRKG
FHRRIKA |
|
¥áv¥â3
heparin |
| Self-renewal & long term expansion |
| H1, H7, H9, H13, H14 |
| Nature Methods (2010) |
|
|
|
Miscellaneous
|
|
TTSWSQCSKS |
|
¥á6¥â1 |
| Self-renewal & long term expansion |
| H1 |
| |
|
|
|
|
|
|
